RECONSIDERING THE USE OF RANKINGS IN THE VALUATION OF HEALTH STATES: A MODEL FOR ESTIMATING CARDINAL VALUES FROM ORDINAL DATA

Reconsidering the use of rankings in the valuation of health states: a model for estimating cardinal values from ordinal data

Abstract Background In survey studies on health-state valuations, ordinal ranking exercises often are used as precursors to other elicitation methods such as the time trade-off (TTO) or standard gamble, but the ranking data have not been used in deriving cardinal valuations.This study reconsiders the role of ordinal ranks in valuing health and intr

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Supercharged chimeric antigen receptor T cells in solid tumors

Chimeric antigen receptor (CAR) T cells have demonstrated success in treating select hematological malignancies, but their activity in solid tumors has been comparably modest.Challenges specific to treating solid tumors include trafficking and distribution throughout the tumor site, overcoming the Shower Heads immunosuppressive tumor microenvironme

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TRC210258, a novel TGR5 agonist, reduces glycemic and dyslipidemic cardiovascular risk in animal models of diabesity

Shitalkumar P Zambad, Davinder Tuli, Anoop Mathur, Sameer A Ghalsasi, Anita R Chaudhary, Shailesh Deshpande, Ramesh C Gupta, Vijay Chauthaiwale, Chaitanya DuttTorrent Research Centre, Torrent Console Fan Pharmaceuticals Ltd, Gujarat, IndiaBackground: Patients with diabesity have a significantly increased risk of developing cardiovascular disea

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